Two women with smooth, glowing skin

Profhilo Skin Booster

The injectable moisturiser.

Profhilo in Manchester

Looking for Profhilo in Manchester? NassifMD Medical Spa is at MediaCityUK, Salford Quays, easy to reach from Manchester city centre, Salford, Trafford and Cheshire. Profhilo is an injectable bio-remodelling treatment that improves skin quality, hydration and elasticity without adding volume or changing your facial shape. Prices start at £350.

We use Profhilo for patients with skin laxity, dehydration, crepey skin and early signs of ageing who want a natural result. It suits both men and women and is commonly used on the face, neck, hands and décolletage.

What is Profhilo?

Profhilo is an injectable treatment made from stabilised hyaluronic acid. It sits within the skin booster category, but works differently from traditional boosters because of its formulation and its deeper biological action.

Rather than simply hydrating, Profhilo spreads through the tissue and stimulates the skin's own production of collagen and elastin while delivering intense hydration. That combination is what improves skin structure, firmness and overall quality — which is why it is described as bio-remodelling rather than filling.

How much does Profhilo cost in Manchester?

Profhilo at NassifMD starts at £350. Because the recommended course is two treatments spaced around four weeks apart, it is worth planning for the full course rather than a single session. Current pricing is on our treatment price list, and your practitioner will confirm the cost of your plan at consultation.

What does Profhilo do?

Hydration

Profhilo attracts and holds water in the deeper layers of the skin, helping restore softness and smoothness.

Skin quality

Texture and tone improve, reducing dullness and uneven surface appearance.

Elasticity

By stimulating collagen and elastin, Profhilo helps restore the skin's natural elasticity and bounce.

Firmness

As new collagen and elastin form, skin gradually becomes firmer and better supported, particularly where early ageing changes have started.

Skin laxity

Profhilo is particularly useful for mild to moderate laxity, improving crepey or thinning skin by strengthening the underlying structure over time.

Importantly, Profhilo is not a dermal filler. It does not add volume, contour features or change facial shape. It improves the quality of the skin itself.

Where can Profhilo be used?

Face

Improves hydration, elasticity and radiance, so skin looks fresher and more rested.

Neck

One of the most popular areas, softening crepey texture, fine lines and loss of firmness.

Décolletage

Targets sun damage and thinning skin across the chest, improving texture and evenness of tone.

Hands

Restores hydration and improves skin thickness, reducing the look of fine lines and visible ageing.

Other areas of laxity or thinning may be suitable depending on your assessment at consultation.

How many Profhilo treatments will I need?

Profhilo is a course, not a one-off. Most patients start with two treatments around four weeks apart, which allows the product to integrate fully while stimulating collagen and elastin.

Early changes in hydration and glow are often noticed within the first few days. The more significant improvements in firmness and texture develop gradually over the following four to eight weeks as the skin remodels.

After the initial course, results typically last several months. Many patients repeat treatment every six to nine months depending on their skin, lifestyle and how quickly their body breaks down hyaluronic acid.

Does Profhilo hurt, and is there downtime?

Profhilo is injected at a small number of precise points rather than across the whole area, which keeps treatment quick — usually 15 to 30 minutes — and generally well tolerated.

Small raised bumps at the injection points are expected and settle within a few hours. Mild swelling, redness, tenderness or occasional bruising can occur and are temporary, usually settling within 24 to 48 hours. Most patients return to normal activities straight away. Your practitioner will go through the risks relevant to you at consultation.

Profhilo compared with other injectable treatments

Profhilo vs dermal fillers

Dermal fillers restore volume, enhance contours and reshape features. Profhilo does neither — it improves hydration, elasticity and skin quality across a broader area. Many patients have both as part of one plan.

Profhilo vs other skin boosters

Traditional skin boosters focus mainly on hydration and surface-level improvement. Profhilo hydrates too, but also stimulates collagen and elastin, producing deeper structural improvement in firmness and elasticity.

Profhilo vs polynucleotides

Polynucleotides work at a regenerative level, supporting cellular repair and the skin's healing and inflammatory response. Profhilo focuses on hydration and bio-remodelling through hyaluronic acid.

Profhilo vs Teoxane Redensity 1

Redensity 1 improves hydration and surface radiance, making it well suited to surface-level skin quality. Profhilo works deeper to improve elasticity, firmness and structure.

Profhilo vs Sculptra

Sculptra is a collagen biostimulator used to restore lost volume gradually over a longer period. Profhilo improves skin quality and firmness without adding volume. They address different problems and are sometimes used together.

Each treatment plays a different role. The right one depends on your skin, your concerns and your goals.

Who is Profhilo suitable for?

Profhilo suits adults who want natural skin improvement without volume enhancement or change to facial shape. It is particularly useful for:

  • Mild to moderate skin laxity and early sagging
  • Dehydrated, dull or tired-looking skin
  • Crepey skin on the face, neck or body
  • Early, preventative treatment
  • Loss of firmness and elasticity
  • Patients who want rejuvenation without fillers
  • Both male and female patients

Your Profhilo treatment at NassifMD

Consultation

Your journey starts with a consultation at our clinic in MediaCityUK, Salford Quays. We assess your skin quality, concerns and suitability before agreeing a plan.

Treatment

Profhilo is administered through a series of precise injection points and typically takes 15 to 30 minutes.

Aftercare

Mild swelling, redness or small raised areas may occur and usually settle within 24 to 48 hours. You will be given aftercare advice, and our aftercare guidance is available to read beforehand.

Results

Improvements develop gradually, with hydration, firmness and elasticity becoming more visible as the skin remodels over several weeks.

Combining Profhilo with other treatments

Profhilo works well alongside HydraFacial, Dermalux LED light therapy, HALO laser and Sciton BBL, and with medical-grade skincare to maintain results between treatments. Combination plans are common where the aim is overall skin quality rather than one isolated concern.

Why choose NassifMD for Profhilo in Manchester?

NassifMD Medical Spa is a medical aesthetics clinic at The Alexandra, 200–220 The Quays, MediaCityUK, Salford, M50 3SP, specialising in advanced injectable treatments and non-surgical skin rejuvenation. We have on-site private parking, and MediaCityUK has its own Metrolink stop, so we are also a short tram ride from Manchester city centre and straightforward to reach from Salford, Trafford and Cheshire.

Our approach focuses on natural, refined improvement in skin quality rather than altering facial structure. Book a consultation or get in touch to ask a question first.

Prices from £350.00

Your Treatment Guide

Expected Results

Plump, glowing skin

Treatment Time

30 minutes

Downtime

Little to none

Longevity

Up to 12 months

FAQs

Profhilo works as both a corrective and a preventative treatment, and suits most adults from around age 30 onwards who want to improve hydration, tone and radiance. It is not suitable for everyone, and suitability is confirmed at your consultation after your skin and medical history are assessed.

Profhilo at NassifMD Medical Spa starts at £350. The recommended initial course is two treatments spaced around four weeks apart, so it is worth planning for the full course. Full pricing is on our treatment price list and confirmed at consultation.

Most patients need an initial course of two treatments, around four weeks apart, which lets the product integrate fully and stimulate collagen and elastin. Some notice improved hydration and glow within a few days, but the clearer improvements in firmness, elasticity and texture develop over four to eight weeks. Results typically last six to nine months, varying with age, skin quality, lifestyle and sun exposure. Maintenance is usually every six to nine months.

Profhilo is injected at a small number of precise points rather than across the whole area, which keeps the treatment short and generally well tolerated. Most patients describe brief stinging at each point. Small raised bumps at the injection sites are expected and settle within a few hours.

Downtime is minimal. Most patients have only mild swelling, redness or small raised bumps at the injection points, which usually settle within 24 to 48 hours. You can normally return to daily activities immediately.

Profhilo improves hydration, skin quality and radiance across an area. Dermal fillers add volume and shape to specific features. They do different jobs, and many patients use both as part of one plan.

Neither is better in general; they work differently. Polynucleotides support cellular repair and the skin's healing and inflammatory response, and are often chosen for delicate areas such as under the eyes. Profhilo focuses on hydration and bio-remodelling to improve firmness and elasticity across a larger area. Your practitioner will recommend based on your skin and goals, and the two are sometimes combined.

Yes. Profhilo works well alongside HydraFacial, laser treatments, Dermalux LED therapy, other skin boosters, polynucleotides and medical-grade skincare. Combination plans are often used where the goal is overall skin quality rather than a single concern.

Small raised bumps at the injection points are normal and settle within a few hours. Mild redness, tenderness or occasional bruising can occur and are temporary. Serious side effects are rare. Your practitioner will explain the risks relevant to you at consultation.

Yes. As well as the face, Profhilo is commonly used on the neck, décolletage and hands, where skin is often thinner and shows crepey texture and loss of firmness. The suitable areas for you are agreed at consultation.

NassifMD Medical Spa is at The Alexandra, 200-220 The Quays, MediaCityUK, Salford Quays, Manchester M50 3SP, with private parking on site and the MediaCityUK tram stop nearby. Patients come to us for Profhilo from across Greater Manchester, Salford, Trafford, Cheshire and further afield. Book a consultation or get in touch and we will talk you through the next steps.