Profhilo is an advanced injectable bio-remodelling treatment designed to significantly improve skin quality, hydration and elasticity without adding volume or altering facial structure.

At Nassif Medspa, a medical aesthetics clinic based in MediaCity, Salford Quays, Profhilo is used for patients experiencing skin laxity, dehydration, crepey skin and early signs of ageing who want natural-looking skin rejuvenation.

Profhilo sits within the injectable skin booster category, but it works in a more advanced way than traditional skin boosters by stimulating both deep hydration and the production of collagen and elastin.

This treatment is suitable for both men and women and is commonly used on the face, neck, hands and décolletage.

What Profhilo Does

Profhilo is an injectable bio-remodelling treatment that belongs to the skin booster category, but differs from traditional skin boosters due to its unique formulation and deeper biological action.

Rather than simply hydrating the skin, Profhilo stimulates the natural production of collagen and elastin while also delivering intense hydration. This combination improves overall skin structure, firmness and quality.

Hydration

Profhilo deeply hydrates the skin by attracting and retaining water within the deeper layers, helping to restore softness, smoothness and overall comfort.

Skin Quality

The treatment improves overall texture and tone, reducing dullness and uneven surface appearance for a healthier, more radiant complexion.

Elasticity

By stimulating collagen and elastin production, Profhilo helps restore the skin’s natural elasticity, improving resilience and bounce.

Firmness

As new collagen and elastin form, the skin gradually becomes firmer and more supported, particularly in areas affected by early ageing changes.

Skin Laxity

Profhilo is particularly effective for mild to moderate skin laxity, helping to improve crepey or thinning skin by strengthening the underlying structure over time.

Importantly, Profhilo is not the same as dermal filler. It does not add volume, contour features or change facial shape. Instead, it improves the biological quality of the skin itself.

Treatment Areas for Profhilo

Profhilo can be used across multiple areas where skin quality has declined due to ageing or environmental factors.

Face

Improves hydration, elasticity and overall radiance, helping the skin appear fresher, smoother and more rested.

Neck

One of the most popular treatment areas, helping to soften crepey texture, fine lines and loss of firmness.

Décolletage

Targets sun damage and thinning skin across the chest, improving texture and restoring a more even tone.

Hands

Restores hydration and improves skin thickness, helping to reduce the appearance of fine lines and visible ageing.

Other Suitable Areas

In selected cases, Profhilo may also be used in additional areas of skin laxity or thinning depending on individual assessment during consultation.

Profhilo vs Other Injectable Treatments

Understanding how Profhilo compares to other injectable treatments helps patients choose the most suitable option for their concerns.

Profhilo vs Dermal Fillers

Dermal fillers are designed to restore volume, enhance contours and reshape facial features. Profhilo does not alter structure or add volume — instead it improves hydration, elasticity and overall skin quality across larger areas.

Profhilo vs Skin Boosters

Traditional skin boosters focus primarily on hydration and superficial skin improvement. Profhilo also hydrates, but goes further by stimulating collagen and elastin production, resulting in deeper structural improvement in skin firmness and elasticity.

Profhilo vs Polynucleotides

Polynucleotides work at a regenerative level, supporting cellular repair and improving skin healing and inflammation response. Profhilo focuses more on hydration and bio-remodelling through hyaluronic acid stimulation.

Profhilo vs Redensity 1

Redensity 1 improves hydration and superficial radiance, making it ideal for surface-level skin quality. Profhilo works deeper within the skin to improve elasticity, firmness and overall structural integrity.

Each treatment plays a different role, and the most suitable option depends on individual skin concerns and goals.

Treatment Plan for Profhilo

Profhilo is not a one-off treatment, but a carefully structured course designed to gradually improve skin quality from within.

Most patients begin with two treatment sessions spaced around four weeks apart. This allows the product to integrate fully within the tissue while stimulating the skin’s natural production of collagen and elastin over time.

Early changes in hydration, glow and skin texture can often be noticed within the first few days after treatment. However, the most significant improvements develop gradually over the following four to eight weeks as the skin remodels itself from within.

Once the initial course is complete, results typically last several months. To maintain optimal skin quality, many patients choose to repeat treatment every six to nine months, depending on their skin condition, lifestyle and ageing process.

With regular maintenance, Profhilo helps to preserve firmness, hydration and elasticity, making it an effective long-term skin rejuvenation treatment rather than a one-off procedure.

Who Is Profhilo Suitable For?

Profhilo is suitable for adults seeking natural skin improvement without volume enhancement or facial alteration.

It is particularly effective for:

• Mild to moderate skin laxity and early sagging
• Dehydrated, dull or tired-looking skin
• Crepey skin on the face, neck or body
• Early preventative anti-ageing treatment
• Loss of firmness and elasticity
• Patients wanting natural rejuvenation without fillers
• Both male and female patients

Your Profhilo Experience at Nassif Medspa

Consultation

Your journey begins with a detailed consultation at our medical aesthetics clinic in MediaCity, Salford Quays. We assess your skin quality, concerns and suitability before creating a tailored treatment plan.

Treatment

Profhilo is administered using a series of precise injection points. The procedure is quick, typically taking 15–30 minutes, and is generally well tolerated.

Aftercare

Mild swelling, redness or small raised areas at injection sites may occur but usually settle within 24–48 hours. Most patients return to normal daily activities straight away.

Results

Improvements develop gradually, with increasing hydration, firmness and elasticity becoming more visible as the skin continues to remodel over several weeks.

Why Choose Nassif Medspa for Profhilo in Manchester?

Nassif Medspa is a medical aesthetics clinic based in MediaCity, Salford Quays, specialising in advanced injectable treatments and non-surgical skin rejuvenation.

Our approach is focused on achieving natural, refined improvements in skin quality rather than altering facial structure or creating artificial volume.

By combining medical expertise, advanced injectable treatments and personalised skincare planning, we help patients achieve long-term improvements in hydration, firmness and overall skin health.